Chemical compatibility

Chemical compatibility for single-use tubing

Search by the chemical’s Danish or English name, formula or a common abbreviation. The result compares the AdvantaPure hoses offered by Alflow with data from the manufacturer’s compatibility table.

AOutstanding
BGod
CLimited
DInsufficient
XNo data in the table

Complete compatibility table

Chemical compatibility at 21 °C for selected AdvantaPure hoses from Alflow
Chemical AdvantaFlex EcoFlex APST APSH-DB APSPH APHP
Acetic acidBBBBBB
AcetoneDDBBBB
AcetonitrileDDDDDD
AcrylonitrileXXDDDD
Ammonium sulphideBBAAAA
BenzeneDDDDDD
BleachAABBBB
Boric acidBBAAAA
Carbon dioxideDDAAAA
ChlorobenzeneDDDDDD
ChloroformDDDDDD
Dichloromethane (DCM)DDDDDD
DiethylamineXXBBBB
Dimethylformamide (DMF)CCBBBB
Dimethyl sulfoxide (DMSO)XXDDDD
DioxaneXXDDDD
EtherDDDDDD
Ethyl acetateDDCCCC
EthanolBBBBBB
Ethylene glycolBBAAAA
FormaldehydeAABBBB
Formic acid 50 %BBCCCC
PetrolDDDDDD
GlycerineBBBBBB
HeptaneCCDDDD
HexanBBDDDD
Hydrochloric acid (HCl) 50 %BBDDDD
Hydrofluoric acid (HF) 50 %AADDDD
Hydrogen peroxide 50 %BBBBBB
YodhDDAAAA
Isopropanol (IPA)BBAAAA
MethanolAAAAAA
Methyl ethyl ketone (MEK)BBDDDD
DichloromethaneDDDDDD
Nitric acid 50 %BBDDDD
PentaneBBDDDD
Perchloric acid 50 %AADDDD
Phenol 50 %DDDDDD
Phosphoric acid 50 %AADDDD
Picric acidDDDDDD
potassium hydroxideAACCCC
Sodium hydroxide 50 %CCBBBB
Sodium peroxideAADDDD
sodium thiosulphateXXAAAA
Sulphuric acid 50 %AADDDD
Tetrahydrofuran (THF)DDDDDD
TolueneDDDDDD
Trifluoroacetic acid (TFA) 50 %XXDDDD
XyleneDDDDDD

Source: AdvantaPure Chemical Compatibility Table (PDF).

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Chemical compatibility for TPE and silicone tubing

How to choose a chemical-resistant hose

Selection of the hose should be based on both the chemical to be transported and the actual process conditions. The chemical resistance of the hose can be influenced by, among other things, the concentration of the chemical, the temperature, the contact time, the pressure and the mechanical stress during operation.

This guide helps you to compare the chemical compatibility of selected TPE and platinum-cured silicone hoses from AdvantaPure. For example, search for isopropanol (IPA), sodium hydroxide (NaOH), dimethyl sulphoxide (DMSO), dimethylformamide (DMF), methyl ethyl ketone (MEK), tetrahydrofuran (THF) or hydrochloric acid (HCl).

The choice between a TPE tubing and a platinum-cured silicone tubing should not be based on the material alone. The construction and application of the tubing also matter. For example, the process may place demands on weldability, flexibility, pressure resistance, mechanical reinforcement or use in a pump.

Therefore, use the search result to identify the most relevant slang types, which can subsequently be evaluated in relation to the overall application.

From compatibility table to validated solution

The compatibility rating shows how the individual hoses are classified in the AdvantaPure chemical compatibility table. A indicates excellent compatibility, B good compatibility, C limited compatibility and D insufficient compatibility. X means that the table does not contain data for the combination in question – not necessarily that the hose is incompatible.

All ratings in the guide are based on test data at room temperature, 70 °F (21 °C). Chemical resistance may change at higher temperatures and is also affected by concentration, contact time, pressure, and other process conditions. A rating cannot therefore stand alone as a final approval of the hose material.

The guide should be considered as a tool for the initial selection. The final hose should be validated under actual operating conditions, and for critical applications, a practical immersion test may be necessary.

Alflow can help match chemical compatibility with requirements for dimensions, pressure, temperature, sterilisation, pumping, connections and documentation, ensuring that the chosen hose suits the entire process.

Frequently asked questions about chemical resistance and hose selection

What do A, B, C, D and X mean in the compatibility table?

A indicates excellent compatibility, B good compatibility, C limited compatibility and D insufficient compatibility. An ‘X’ means that the AdvantaPure table does not contain data for the combination in question. An ‘X’ therefore does not necessarily mean that the hose is incompatible.

How does temperature affect the chemical resistance of the hose?

Compatibility ratings in the guide apply at room temperature, 70 °F (21 °C). At higher temperatures, the chemical resistance of the hose material may change. The result should therefore always be evaluated based on the actual temperature in the process.

Does the concentration of the chemical matter?

Yes. A tube material can react differently to diluted and concentrated solutions. Contact time, pressure, temperature and mechanical stress can also alter the suitability of the tube. Therefore, use the concentration shown in the table as a reference.

What is the difference between a TPE and a silicone tubing?

TPE tubing is often used when the process requires a weldable and sealable tube for a single-use system. Platinum-cured silicone tubes are flexible and available in various designs for, amongst other things, fluid transfer, higher pressures, and mechanical reinforcement. The final choice depends on both chemical compatibility and process requirements.

Which hose can be used for isopropanol or IPA?

Search for “IPA”, “isopropanol” or “isopropyl alcohol” in the guide. The results show the AdvantaPure’s compatibility rating for each of the hoses displayed. The choice of hose must also be assessed in relation to concentration, temperature, contact time, pressure and application.

How do I find a hose for NaOH, DMSO, DMF or other chemicals?

You can search using both the chemical's name and common abbreviations such as NaOH, DMSO, DMF, MEK, THF and HCl. The guide compares the available ratings for the displayed TPE and silicone tubing.

Can the compatibility table replace a practical test?

No. The table is a tool for preliminary selection and not a guarantee that a hose is suitable for a specific process. For critical applications, the material should be validated under actual operating conditions. An immersion test may be necessary.

What information does Alflow need to help with hose selection?

It is an advantage to know the chemical, concentration, temperature, contact time, desired flow rate, operating pressure, hose dimensions, and any requirements for pumping, sterilisation, connections, and documentation.