Compare AdvantaPure single-use and bioprocessing tubing

Choosing the right tubing is of great importance in pharma, biotech and single-use processes. The tubing must not only be suitable for the medium, but also for the requirements regarding sterility, flexibility, documentation, pressure, temperature and the way it is incorporated into the process.

AdvantaPure offers hose solutions for demanding applications where purity, traceability and process control are crucial. The range includes, among other things, TPE hoses and silicone hoses for sterile liquid transfers, single-use processes, peristaltic pumps and other critical pharma and bioprocessing applications.

Which single-use tubing is suitable for your process?

When choosing tubing for a single-use application, it is important to look at the entire process. Is the tubing to be used for fluid transfer, filling, sampling, buffer/media transfer or as part of a complete assembly? And does it need to be weldable, sealable, autoclavable or supplied sterile?

Typical factors you should consider are:

• Whether the tubing is for single-use or repeated use
• Whether there are requirements for sterility, autoclaving or gamma irradiation
• If the tube is to be weldable or sealable
• Which medium the hose is to transport
• Temperature and pressure conditions in the process
• Requirements for flexibility, kink resistance and pump characteristics
• Need for documentation, traceability and batch-specific certificates
• If the hose is to be part of a complete assembly with fittings, clamps, connectors or sterile couplings

AdvantaFlex – TPE tubing for single-use fluid transfer

AdvantaFlex is a TPE tubing often used in single-use applications where a flexible, documented and efficient solution for fluid transfer is needed. It may be relevant in processes where the aim is to reduce cleaning, minimise the risk of cross-contamination and simplify handling between batches.

TPE tubing such as AdvantaFlex is typically used in bioprocessing, filling, sampling and sterile transfer applications where the tubing forms part of a closed or semi-closed system. It can be an obvious choice when welding, sealing and single-use handling are important parameters in the process.

AdvantaSil – silicone hose for pharma and bioprocessing

AdvantaSil is a silicone hose developed for applications where flexibility, purity and documentation are key requirements. Silicone hoses are often used in pharma and biotech processes where the hose must be easy to handle while meeting high standards for material quality and traceability.

Silicone tubing can be relevant for fluid transfer, laboratory equipment, peristaltic pumps and process steps where flexibility and pumping properties play an important role, among other things. They can also be a good choice in applications where the tubing must be handled repeatedly or form part of more flexible process setups.

TPE or silicone – which should you choose?

Both TPE and silicone tubing can be relevant in single-use and bioprocessing, but they have different strengths.

TPE tubing is often chosen when the focus is on single-use, welding, sealing and efficient handling between batches. Silicone tubing is often chosen when there is a need for high flexibility, good pump performance and broad application in pharma and biotech processes.

The right choice therefore depends on the specific application. A tube for sterile fluid transfer does not necessarily have the same requirements as a tube for peristaltic pumping, sampling or filling. Therefore, material selection, documentation and process requirements should always be evaluated together.

Documentation is an important part of the election

In the pharma and biotech industries, documentation is often just as important as the hose itself. Therefore, you should not only compare hoses on material and technical data, but also on the documentation that comes with them.

Depending on the application, it may be relevant to review documentation regarding biocompatibility, extractables/leachables, food contact, traceability, sterility and batch-specific certificates. This can be of great importance in connection with qualification, validation and audits.

Use the comparison as a first step

A comparison of AdvantaPure hoses gives a good overview of the options, but the final solution should always be assessed based on the specific process. Small differences in medium, temperature, pressure, pump setup, fittings or sterilisation method can affect which hose is best suited.

At Alflow, we help you find the right hose solution based on application, documentation requirements, and practical use. We can also help assess whether the hose should be supplied as a standard product, customised with fittings, or be part of a complete single-use assembly.

If you need help choosing between AdvantaPure hoses, you can contact us for advice on the solution that best suits your process.